A bifunctional protein regulates mitochondrial protein synthesis
نویسندگان
چکیده
منابع مشابه
A bifunctional protein regulates mitochondrial protein synthesis
Mitochondrial gene expression is predominantly regulated at the post-transcriptional level and mitochondrial ribonucleic acid (RNA)-binding proteins play a key role in RNA metabolism and protein synthesis. The AU-binding homolog of enoyl-coenzyme A (CoA) hydratase (AUH) is a bifunctional protein with RNA-binding activity and a role in leucine catabolism. AUH has a mitochondrial targeting sequen...
متن کاملMitochondrial protein acetylation regulates metabolism.
Changes in cellular nutrient availability or energy status induce global changes in mitochondrial protein acetylation. Over one-third of all proteins in the mitochondria are acetylated, of which the majority are involved in some aspect of energy metabolism. Mitochondrial protein acetylation is regulated by SIRT3 (sirtuin 3), a member of the sirtuin family of NAD+-dependent protein deacetylases ...
متن کاملDisorders of mitochondrial protein synthesis.
Mitochondrial tRNA gene mutations, including heteroplasmic deletions that eliminate one or more tRNAs, as well as point mutations that may be either hetero- or homoplasmic, are associated with a wide spectrum of human diseases. These range from rare syndromic disorders to cases of commoner conditions such as sensorineural deafness or cardiomyopathy. The disease spectrum of mutations in a given ...
متن کاملSynchronization of Energy and Protein on Supply Synthesis Microbial Protein
Synchronization of rumen available protein and energy is one of the conceptual methods to increase the efficiency of utilization of nutrients by the ruminants The concept of synchronization energy and protein was first by Jhonson, Implying that maximum microbial protein synthesis could be achieved by matching the rate of Organic Matter and protein degradation. Synchronization of rumen available...
متن کاملSynchronization of Energy and Protein on Supply Synthesis Microbial Protein
Synchronization of rumen available protein and energy is one of the conceptual methods to increase the efficiency of utilization of nutrients by the ruminants The concept of synchronization energy and protein was first by Jhonson, Implying that maximum microbial protein synthesis could be achieved by matching the rate of Organic Matter and protein degradation. Synchronization of rumen available...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2014
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gku179